mood disorder questionnaire scholarly articles
Patients fulfilling the study criteria were invited to participate in the study. Article KS supervised the fieldwork, interviewed patients, and participated in writing the paper. Nevertheless, our prevalences of positive items (27–74% vs. 34–77%) and bipolar disorder (53% vs. 55%) were similar to the original validation study figures, although the proportion of type II disorder was higher (50% vs. 24%) in ours. The Mood Disorder Questionnaire seems to be a feasible method for improving the recognition of bipolar disorder. The Mood Disorder Questionnaire (MDQ) is a well-recognized screening tool for bipolar disorder, but its Chinese version needs further validation. For more information about PLOS Subject Areas, click Receiver Operating Characteristic(ROC) curves were used to determine the ability of the MDQ to differentiate between BD (BD, BD-I and BD-II) and MDD or UD and patients with BD-I from patients with BD-II. 1978, 226: 57-64. If the MDQ was negative, the attending professional was also asked whether bipolar disorder might be present despite a negative screen (clinical suspicion). Discover a faster, simpler path to publishing in a high-quality journal. Secondly, the sensitivities 0.22 (or 0.24) were too low to screen at cutoffs 7 (or 6) for a screening tool. However, the optimal cut-off within this sample was found to be eight symptoms but accepting also minor problems due to episodes (sensitivity 0.90, specificity 0.59). Of the 1,487 patients, 309 (20.8%) satisfied the DSM-IV criteria for BD: 118 (7.9%) for BD-I and 191 (12.8%) for BD-II. Explore the adjustment disorder symptoms that are experienced by the patient (e.g., excessive worry about a current stressor, sad mood, decreased sleep, re-duced appetite). The translated MDQ was found internally consistent (alpha 0.79) and a feasible screening tool. The first question includes 13 items, symptoms or behaviors related to a manic or hypomanic syndrome. In practice, many patients with BD experience a delay in initiating treatment or are given the wrong treatment because of the under-recognition and frequent misdiagnosis of this disorder –. https://doi.org/10.1371/journal.pone.0091895.g005. A depressive episode is not required for BD-I diagnosis, but it frequently occurs. The American Psychiatric Association's (APA) Diagnostic and Statistical Manual of Mental Disorders, Fifth Editionadded a peripartum onset to the psychiatric mood disorder category. Many children show mood disorders, anxiety, learning problems along with conduct disorder symptoms. Further, the reliability of the diagnostic procedure was not formally tested. Forty subjects (37%) were positive in the MDQ. Take this bipolar test to see if you might have bipolar disorder symptoms. mood dysregulation disorder among children and adolescents is estimated to fall into the 2%–5% range (APA, 2013). Peking University Institute of Mental Health, Beijing, China, Affiliation statement and Adapted from Hirschfeld R, Williams J, Spitzer RL, et al. The term depression is often used to refer to any of several depressive disorders. Is the Subject Area "Bipolar disorder" applicable to this article? Fourth Edition, Text Revision. The criterion validity of the MDQ was estimated using the SEN, SPE, positive predictive value (PPV), negative predictive value (NPV) and the area under the curve (AUC). Wrote the paper: HCY. Part three assesses the level of functional impairment due to the symptoms on a 4-point scale (“no” to “severe”) , . We investigated our translation of The Mood Disorder Questionnaire (MDQ) as a screening instrument for bipolar disorder in a psychiatric setting in Finland. Mental Health Institute, The Second Xiangya Hospital, Central South University, Hunan, China, Affiliation Eating disorders (EDs) are serious psychiatric illnesses that have high rates of morbidity and mortality, and low long-term recovery rates. In the reliability exercise, raters' judgments of BD were compared with the best estimate clinical diagnoses ; the kappa values were above 0.85 for each rater. No, PLOS is a nonprofit 501(c)(3) corporation, #C2354500, based in San Francisco, California, US, https://doi.org/10.1371/journal.pone.0091895. Our study population was not a selected sample of patients with mood disorders, but rather an ordinary sample of secondary care … Patients then underwent a DSM-IV diagnostic interview using the MINI by a rater who was blind to the C-MDQ results. J Affect Disord. Shanghai Tongji Hospital, Tongji University Medical School, Shanghai, China, Affiliation Washington, DC, American Psychiatric Association. PLOS ONE promises fair, rigorous peer review, Angst J, Felder W, Frey R, Stassen HH: The course of affective disorders: I. Correspondence to Cite this article. Although the definite cutoffs were different, this study demonstrated again that the MDQ could screen patients with BD-I from patients with BD-II, and patients with BD-II from UD . Secondly, because impairment in functioning is not necessary to diagnose hypomania, requiring impairment on the MDQ to determine BD will reduce its sensitivity for detecting BD-II . We suggest that the best screening cutoff between BD-II and UD could also be used as the optimal cutoff between BD and UD to improve screening for BD-II . All members of the research team were qualified psychiatrists. Hirschfeld RMA, Lewis LL, Vornik LA: Perceptions and impact of bipolar disorder: How far have we really come? This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Both in- and outpatients experiencing a major depressive episode were enrolled if they were between 16 and 65 years of age, had a DSM-IV or ICD-10 diagnosis of MDD based on a review of their medical records, understood the aims of the study and provided informed consent. 1997, Washington, DC, American Psychiatric Press. The Mood Disorder Questionnaire  is a short self-report screening instrument, and was translated into Finnish by the authors. In part one, the MDQ screens for a lifetime history of manic/hypomanic symptoms using 13 yes/no items. Thank you for your inquiry about the Mood and Feelings Questionnaire (MFQ), developed by Adrian Angold and Elizabeth J. Costello in 1987. Bipolar disorder not otherwise specified (BD-NOS) is a catchall category, diagnosed when the disorder does not fall within a specific subtype. This was a pilot study for the current Jorvi Bipolar Study (JoBS). Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, Shanghai, China, Affiliation The Chinese version of the MDQ (C-MDQ) has been validated in China . Bipolar disorder (BD), as defined by modern classification systems, encompasses episode of mania/hypomania and usually depression. Against a SCID diagnosis of bipolar I or II by trained research interviewers used as the “gold standard,” the sensitivity was 28.1% and the specificity was 97.2%. © 2021 BioMed Central Ltd unless otherwise stated. There were no significant differences between the enrolled patients and patients who did not participate in terms of age and sex. As per the scoring guidelines, if you answer "yes" t… The results of the Korean study were similar to ours. Whether screening is actually beneficial is related to the quality of current routine diagnostic procedures. Change of diagnosis of monopolar, unipolar and bipolar illness. In most studies concerning the MDQ, including the earlier study in China, testing of subjects with mood disorders was not restricted to the depressive phase , –. As the predominant psychopathology even in treated BD, depression is associated not only with excess morbidity, but also mortality from co-occurring general-medical disorders and high suicide risk. Am J Psychiatry. The whole JoBS project has been evaluated and accepted in the Ethics Committee of the Helsinki and Uusimaa Hospital District, and it complies with the principles of the Helsinki Declaration. Am J Psychiatry. The best cutoffs maximizing the sums of the SEN and SPE were calculated for the MDQ to discriminate between MDD and BD, between BD-II and BD-I, and between MDD and BD-II. 2003, 160: 178-180. Symptoms may include extreme sadness, low energy, anxiety, crying episodes, irritability, and changes in sleeping or eating patterns. There was a significant difference among the scores of depressive patients with BD-I, BD-II or UD based on one-way analysis of variance (P<0.01, ANOVA). Therefore, it was necessary to study the response of the patients with mood disorders to the MDQ during their depressive phase. The aim of this study was to test the ability of the Chinese version of the Mood Disorder Questionnaire (MDQ) to identify Bipolar Disorders (BD) in patients diagnosed with Major Depressive Disorder (MDD) or Unipolar Disorder (UD) in the clinical setting. Yes The Diagnostic Assessment Service for People with Bipolar Disorders in China (DASP) is an ongoing national study initiated by the Chinese Society of Psychiatry (CSP) with the aim of developing and testing the usefulness of screening tools for BD in patients treated for MDD. Depression. The study protocol was approved by the Clinical Research Ethics Committees of the respective study centers. Having minor problems might be enough. BMC Psychiatry The Mood Disorder Questionnaire (MDQ) is an excellent screening tool for bipolar disorder.It is considered a gold standard screening tool in the world of bipolar disorder. 10.1016/0165-0327(92)90044-7. Clinical trials have indicated that the MDQ has a high rate of accuracy; it is able to identify seven out of ten people who have bipolar disorder and screen out nine out of … The internal consistency of the translated instrument was almost as good (Cronbach's alpha 0.79 vs. 0.90) as in the original validation study . The diagnosis of BD-II need one or more hypomanic episodes (without manic episode) and one or more major depressive episode. No, Is the Subject Area "Psychometrics" applicable to this article? Our findings support the value and feasibility of screening for bipolar disorder with the MDQ in psychiatric settings. There were two limitations in the study. This is not unexpected because the test-retest reliability (or kappa) of the SCID in the … It was not clear if all three parts of the MDQ could be used in clinical settings in China. The questionnaire takes about five minutes to complete, and can provide important insights into diagnosis and treatment. Thirdly, the results of this multicenter study were similar to those of the earlier study that was limited to two psychiatric hospitals in China. here. In a pilot study for the Jorvi Bipolar Study (JoBS), 109 consecutive non-schizophrenic psychiatric out- and inpatients in Espoo, Finland, were screened for bipolar disorder using the Finnish translation of the MDQ, and 38 of them diagnostically interviewed with the SCID. Some studies have proposed modifying the MDQ scoring by ignoring part three and lowering the threshold screening for BD. When all three parts were used, the MDQ could not be used as a screening tool in clinical settings. Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland, Erkki Isometsä, Kirsi Suominen & Sami Leppämäki, Department of Psychiatry, Jorvi Hospital, Helsinki University Central Hospital, Espoo, Finland, Kirsi Suominen, Outi Mantere, Hanna Valtonen, Sami Leppämäki, Marita Pippingsköld & Petri Arvilommi, You can also search for this author in Mood disorders may increase your risk of suicide. 1998, 50: 163-173. The most important public health problem related to bipolar disorder is the remarkable proportion of patients who have unrecognised bipolar II disorder [6–10]. Erkki Isometsä. 2000, 61: 804-08. The Department has a catchment area of approximately 250 000 inhabitants, but this pilot study was conducted only in two selected community mental health centres (Leppävaara and Kirkkonummi), and in the psychiatric outpatient clinic of Jorvi Hospital and three of its psychiatric wards. Twenty‐one studies were included. Bipolar disorder (BD), also known as bipolar affective disorder or manic-depressive disorder. If the best cutoff of 6 between BD-II and UD was used as the optimal screening cutoff between BD and UD, the MDQ could not differentiate BD patients from UD when all three parts of the MDQ were used in the ROC curve analysis (P>0.05, AUC 0.60, SEN 0.24, SPE 0.96, PPV 0.58, NPV 0.83, Figure 5). The screen thus influenced whether a diagnostic interview was conducted. Firstly, by the ROC curve analysis, the MDQ could not screen BD patients from UD patients when either 7 or 6 was regarded as the optimal cutoff. Any of several psychological disorders characterized by abnormalities of emotional state and including especially major depressive disorder, dysthymia, and bipolar disorder—called also affective disorder. The instrument has so far been little investigated by others than its developers. In our diagnosed sample, accepting minor impairment too, but necessitating eight symptoms, was found to be the optimal cut-off. The subspecialties of psychiatry and gynecology have developed overlapping but distinct diagnoses that qualify as a premenstrual disorder… Still, mood phases may have an impact on the results of these self-rating questionnaires , . Approximately 75% of adolescents in the US1 and more than 90% in Korea2 and Japan3 sleep less than the recommended 8–10 h a night.4 Previously, the maturational delay in bedtime combined with early morning school were the principal reasons for shortened sleep in adolescence.5 In recent years, increased electronic media use, higher homework load, and reduced parental control have … The National Depressive and Manic-Depressive Association 2000 survey of individuals with bipolar disorder. The feature of relatively low sensitivity (0.66) and higher specificity (0.88) in this study was similar to that of other studies as well , , –. The sensitivity was considerably less than that found in the psychiatric outpatient group. Analyzed the data: HCY XPW. (1, 2, 3) 1. What are the symptoms of common mood disorders? After giving consent, patients were invited to complete the C-MDQ. Three patient groups were screened: (a) all new patients who were referred to treatment in the Department of Psychiatry; (b) all patients who had earlier received treatment in the Department, but now had a new referral, and (c) those already in contact with the facilities, without a clinical diagnosis of ICD-10 schizophrenia, and now showing signs of deteriorating clinical state after at least two months of limited or no symptoms. Demographics and illness characteristics of the first 261 patients. Mood Disorder Questionnaire (MDQ) The Mood Disorder Questionnaire (MDQ) includes 13 questions associated with bipolar disorder symptoms and is available in Spanish. Agitation, restlessness, or irritability. The internal consistency of the translated instrument was found to be good (Cronbach's alpha 0.79). We found the Mood Disorder Questionnaire to be a feasible method for improving recognition of bipolar disorder, which has clearly been a problem. 1.2 Mental Health Disorders and Human Capital Formation The subjects with BD in this study may not be representative of all BD patients. https://doi.org/10.1371/journal.pone.0091895.g002. https://doi.org/10.1371/journal.pone.0091895.g001. Hantouche EG, Akiskal HS, Lancrenon S, Allilaire J-F, Sechter D, Azorin J-M, Bourgeois M, Fraud J-P, Chatenet-Duchene L: Systematic clinical methodology for validating bipolar II disorder: data in mid-stream from a French national multi-site study (EPIDED ). Altogether, 1,757 patients were invited to participate in this study; 270 refused to participate or failed to complete the interview. OM, HV, SL, MP and PA interviewed patients and commented on the manuscript. Click through the PLOS taxonomy to find articles in your field. The MINI is a short, structured diagnostic interview that was developed jointly by psychiatrists and clinicians for DSM-IV psychiatric disorders. Thus the last question in the MDQ, necessitating moderate to severe problems due to episodes, appears to have a higher threshold for impairment. Their mean age was 37.9 ± 11.4 years, and 56 (51%) were female. There are disagreements with respect to the scoring of the MDQ. OBJECTIVE: This study tested the validity in the adult general population of the Mood Disorder Questionnaire, a screening instrument for bipolar I and II disorders.The Mood Disorder Questionnaire has been validated in a psychiatric outpatient study group. Bipolar disorder, particularly type II, remains commonly unrecognized in psychiatric settings. 1992, 26: 127-140. The MDQ could differentiate BD patients from UD patients when only part one was used in the ROC curve analysis (P<0.05, Figure 1). Postpartum depression (PPD), also called postnatal depression, is a type of mood disorder associated with childbirth, which can affect both sexes. The AUC was 0.84. All interviewers were either psychiatrists or residents with several years experience in psychiatry and relevant training. The change of MDQ score in patients with mood disorders was similar to that of the earlier Chinese study, which did not limit patients to the depressive phase . Ignoring severity of problems caused (question three) altogether resulted in very low specificity. Manage cookies/Do not sell my data we use in the preference centre. The Mood Disorder Questionnaire improves recognition of bipolar disorder in psychiatric care. Again, when only part one of the MDQ was used, the best screening cutoff between BD-I and BD-II was 10, a different finding from the cutoff of 8 in the earlier study from China. Take the Mood Disorders Questionnaire before reading this scoring page.. Determine what stressors are present and the time course of These settings were evenly distributed in China and served both catchment area patients and patients from neighboring areas. J Affect Disord. Table 1 displays the socio-demographic characteristics of the whole sample and separately for patients by diagnosis. Sensitivity was 0.64, specificity was 0.80 and the area under curve was 0.75 at the optimal screening cutoff between BD and UD . J Affect Disord. Conceived and designed the experiments: TBL LJL XPW. Copyright: © 2014 Yang et al. 2003, 73: 59-64. We used a bivariate random effects model to calculate summary sensitivity and specificity. No, Is the Subject Area "Diagnostic medicine" applicable to this article? 10.1016/S0165-0327(01)00432-3. Whether necessitating moderate to severe problems to be caused by it is useful in screening should be further investigated. Because the treatments of different types of mood disorders and subtypes of bipolar disorders are different, MDQ which help clinicians in differentiating mood disorders is useful in practice. DESCRIPTION: The MFQ consists of a series of descriptive phrases regarding how the subject has been feeling or acting recently.Codings reflect whether the phrase was descriptive of the subject most of the time, sometimes, or not at all in the past two weeks. The mean ages of the two groups were 38.2 ± 8.0 years and 39.1 ± 12.5 years, respectively. http://www.biomedcentral.com/1471-244X/3/8/prepub. https://doi.org/10.1371/journal.pone.0091895.g004. In the vast majority of those reporting seven or more items, several symptoms had occurred within the same time period (in 87%), and moderate to serious problems were present (in 91%). Exclusion criteria included a past diagnosis of BD, ongoing significant medical or neurological condition(s), depressive disorders secondary to a general medical or neurological condition, or having received electroconvulsive therapy (ECT) in the past month. PubMed Given the relatively good resources and interest in bipolar disorder in the Jorvi psychiatric facilities, we expect recognition to be at least not worse than elsewhere in Finland. The sample of patients screened with the Mood Disorder Questionnaire was not large (N = 109), albeit probably representative of psychiatric in- and outpatients in the area. In the present pilot study, using our Finnish translation of the Mood Disorder Questionnaire among unselected psychiatric patients, we investigated its psychometric and screening properties, and its feasibility in improving recognition of type I and II bipolar disorder. Peer mentor programs (PMPs) have been associated with reduced psychiatric hospitalisation and shorter lengths of stay for those with other severe mental illnesses. Of those eligible for diagnostic interview, 38 of 51 (75%) agreed to participate. Section edited by Florian Seemüller. The study population consisted of 29,133 male smokers aged 50 to 69 years who entered the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in 1985–1988. Individuals with BD experience episodes of an elevated or agitated mood known as mania/hypomania alternating with episodes of depression. It asks: 1. if you've experienced any of 13 specific behaviors associated with bipolar disorder 2. if the symptoms you checked in question one occurred at the same time 3. about the severity of your symptoms 4. about your family's history of mental illness 5. if you've previously been diagnosed with a mental illness You can view the full questionnaire on the Depression and Bipolar Support Alliancewebsite. The internal consistency (Cronbach's alpha) of the C-MDQ was 0.79. This study aims to measure the accuracy of the Chinese version of the MDQ as a screening instrument for bipolar disorder (BPD) in a group of patients with a current major depressive episode. The Mood Disorder Questionnaire is a feasible screen for bipolar disorder, which could well be integrated into psychiatric routine practice. By using this website, you agree to our All patients who participated in this study completed written consent forms. J Clin Psychiatry. https://doi.org/10.1186/1471-244X-3-8, DOI: https://doi.org/10.1186/1471-244X-3-8. The majority of unrecognised patients in our sample, too, had bipolar II disorder. The Mood Disorder Questionnaire appears to be a feasible method for improving the recognition of bipolar disorder. The number of patients interviewed with SCID was relatively small. The funders had no role in study design, data collection and analysis,decision to publish, or preparation of the manuscript. Some studies ,  have found that the MDQ may be insensitive in the detection of BD due to the items in part three. BMC Psychiatry 3, 8 (2003). Of the self-rating mania/hypomania questionnaires developed to screen for BD , , the Mood Disorder Questionnaire (MDQ) is one that has been used effectively in many countries , –. Patients with BD in the depressive phase have difficulty recalling past manic/hypomanic symptoms . https://doi.org/10.1371/journal.pone.0091895.t001. Competing interests: The authors have declared that no competing interests exist. Women may experience many types of psychiatric problems after childbirth. Our study population was not a selected sample of patients with mood disorders, but rather an ordinary sample of secondary care psychiatric patients, schizophrenia excluded. J Affect Disord. AstraZeneca China had no role in the study design or in the generation and interpretation of the results. The screen is regarded positive when seven or more positive symptoms have occurred, several within the same episode, causing moderate to severe problems. The study was initiated by the Chinese Society of Psychiatry (CSP) with support from AstraZeneca China. In the ROC-analysis (Table 2, Additional file: 1) with the standard cut-offs, sensitivity emerged as high (0.85), but specificity only moderate (0.47). The Chinese version of the MINI showed strong reliability and validity in eliciting symptom criteria used to make DSM diagnoses . Finally, the generalizability of our findings within Finland, or to other countries, is not known. All patients with a positive screen or clinically suspected of having bipolar disorder were invited to be interviewed with the Structured Clinical Interview for DSM-IV Axis I Disorders, Clinician Version, SCID-CV . This refers to a major depressive episode with an onset during pregnancy or following childbirth. Hypomanic episode do not go to the full extremes of mania (i.e., do not usually cause severe social or occupational impairment, and are without psychosis), and this can make BD-II more difficult to diagnose, since the hypomanic episodes may simply appear as a period of high productivity and creativity. It is therefore clear that the ROC-analysis overestimated sensitivity and underestimated specificity, and cannot be compared with respective estimates from unselected samples . We conducted this study to determine (1) which parts of the Chinese version of the MDQ should be used to screen for BD in the clinical setting; (2) compare the use of the MDQ for patients during the depressive phase with a previous study in which the MDQ was administered during any phase (mania, depression) and (3) determine if the results of our previous study of the MDQ in two psychiatric hospitals could be replicated in other centres which included psychiatric clinics and general hospitals across China. here. Depression in bipolar disorder (BD) patients presents major clinical challenges. CAS BD is a common disorder. Panic disorder is characterized by the spontaneous and unexpected occurrence of panic attacks, the frequency of which can vary from several attacks per day to only a few attacks per year. Ultimately, 1,487 patients were included in the analysis. Hangzhou Seventh People's Hospital, Zhejiang, China, Affiliation The second question asks whether several of the symptoms have been experienced during the same time period, and the third asks about resulting problems, classified as minor, moderate or serious. Division of Mood Disorders, Shenzhen Mental Health Centre, Shenzhen Key Lab for Psychological Healthcare, Guangdong, China, * E-mail: email@example.com (TBL); firstname.lastname@example.org (LJL), Affiliation 2000, 157: 1873-1875. Yes Then please print the test results and consider sharing them with your doctor or therapist. West China Hospital, Sichuan University, Sichuan, China, Affiliation The mean MDQ score for BD patients was significantly higher than that of UD; BD-I was higher than BD-II, and BD-II was higher than UD (t-test, P<0.01). Using the SCID-interview as the gold standard, the MDQ screening produced 9 false positives (5 patients with unipolar MDD; one schizoaffective, brief psychotic, and personality disorders; plus an amphetamine-induced psychosis) and three false negative patients (one type I with < 7 acknowledged items, one type II patient with only minor problems due to hypomania, and one type II with both). Despite the small sample size, the difference approached statistical significance (Fisher's exact test, p = 0.07). For more information about PLOS Subject Areas, click Mood Disorders Mood disorders is a psychological disorder characterized by the elevation or lowering of a person's mood, such as depression or bipolar disorder. Depressive Disorders. Designed for screening purposes only and not to be used as a diagnostic tool. The MDQ could differentiate BD-I patients from BD-II when only part one was used in the ROC curve analysis (P<0.05, AUC 0.60, Figure 3) and the best screening cutoff between BD-I and BD-II was 10 (SEN 0.37, SPE 0.83, PPV 0.58, NPV 0.59). J Affect Disord. Benazzi F, Akiskal HS: The dual structure of self-rated MDQ hypomania: energized-activity versus irritable-thoughts racing. Some major factors involve child abuse or neglect, school failure, traumatic life experiences and brain damage. Bipolar disorders cause role impairment and high mortality and economic burden . For the ongoing Jorvi bipolar study ( JoBS ) all BD patients Neuropsychological testing '' applicable to this article fall! No competing interests exist all BD patients peer mood disorder questionnaire scholarly articles, broad scope, and in! Much money or driving recklessly determine what stressors are present and the time of. 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Necessitating eight symptoms, was found to be good ( Cronbach 's alpha ) of the illness behaviour.
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